The Giants Rams matchup headlines Week 2 of the NFL season on Monday Night Football. The Los Angeles Rams, who came into the season as the favorite to win Super Bowl 61, are hosting the New York Giants, who are coming off an impressive Week 1 win over the Dallas Cowboys. Before the season started, the Rams would have been guaranteed a win in this game, but that doesn’t seem to be the case anymore. There are plenty of overreactions about each team’s week one performance, but none of that will matter when the game begins in prime time (2nd primetime game in a row for each team).
Rams Really Need A Bounce Back Game
Opening the season in Australia against the San Francisco 49ers, the Rams were disappointing from start to finish. Their only score came in the second quarter, when Kyren Williams rushed for a touchdown, before the 49ers scored 24 unanswered points.
Offensively, quarterback Matthew Stafford did not play to his MVP level from last season, finishing with a 61.2 passer rating, completing 15 of 25 passes, and throwing an interception. He was benched in the fourth quarter for backup Stetson Bennett.
2025 Defensive Player of the Year Myles Garrett was shut down by 49ers tackle Trent Williams, left the game with an injury, and will miss the next four weeks on injured reserve.
The Rams are stateside again and will enter the game having gotten plenty of rest. Despite their struggles in week one, they still sport an elite offense and should not be taken lightly.
Giants Have The Pieces Together

The Giants won their first week one home opener since 2010, and under new head coach John Harbaugh, began a season 1-0 for the first time since 2022. They scored four touchdowns against the Cowboys, after three consecutive openers without a touchdown.
New York’s offense impressed, starting with the time of possession. They held the ball for 20:59 in the second half (compared to 8:27 for Dallas), going nine of 10 on third downs before the final kneel.
Quarterback Jaxson Dart found six different receivers during the game, highlighted by tight end Isaiah Likely, who had eight receptions for 78 yards and two touchdowns. Fullback Patrick Ricard did not record a single carry, but his blocking opened holes for Cam Skattebo, who finished with 81 yards and a touchdown.
This Giant team has plenty of confidence entering Monday night’s matchup in Los Angeles, and if the offense continues to be patient and controls the clock, New York will leave the game with its first 2-0 start in four years. After the Rams, they have a pretty favorable schedule before the bye, with the toughest matchup being against the Houston Texans in Week 7.
Prediction For Giants Rams Week 2 Game
The main talking points are mentioned, so here’s a prediction. According to DraftKings Sportsbook, the Rams are favored by seven points on Monday Night, which is a little bit of a surprise.
There will be plenty of big offensive plays that can make this game exciting. Stafford has the receiving targets in Puka Nacua and Davante Adams, but he can use Kyren Williams in that end too. Dart also has a lot to work with, bringing in Cam Skattebo from the backfield, but can include star receiver Malik Nabers, rookie Malachi Fields, and Isaiah Likely as important targets.
This game could finish in a one-score battle, with both teams really putting up a fight.
